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Showing posts with the label Covishield

Billionaire Poonawalla family pledges $66 mn to Oxford for research campus

  The pledge builds on the collaboration between   Oxford University , AstraZeneca and SII, the world’s largest maker of vaccines Vaccine maker Serum Institute of India (SII) has pledged 50 million pounds ($66.2 million) to the University of Oxford for setting up a research campus that would also house the institute behind the  AstraZeneca -Oxford COVID-19 shot. The investment was made through the Indian company’s Serum Life Sciences unit, Oxford University said on Wednesday. The research building would be named after Serum’s billionaire owners, the Poonawalla family. The pledge builds on the collaboration between Oxford University, AstraZeneca and SII, the world’s largest maker of vaccines and the producer of a version of the British duo’s COVID-19 shot for low- and middle-income countries. SII has also agreed with the Jenner Institute, which was behind the Oxford-AstraZeneca COVID-19 vaccine, to produce and develop Jenner’s R21/Matrix-M malaria shot on a large scale. Th...

Covaxin doses 50% effective against symptomatic Covid: Real-world study

  Research does not estimate vaccine effectiveness against hospitalisation, severe disease, and death. Two doses of Covaxin, the India-made vaccine, are 50 per cent effective against symptomatic Covid-19, said an independent study by researchers based on real-world assessment . Results of the interim study, which was published in The Lancet Infectious Diseases Journal, showed that two doses of the vaccine manufactured by  Bharat Biotech Covaxin , also known as BBV152, had 77.8 per cent efficacy against symptomatic disease and present no serious safety concerns.. The study titled ‘Effectiveness of an inactivated virus-based SARS-CoV-2 vaccine, BBV152, in India: a test-negative, case-control study’ assessed 2714 hospital workers at the All India Institute of Medical Sciences (AIIMS) in Delhi, from April 15–May 15, who were symptomatic and underwent RT-PCR test for  Covid-19  detection. The researchers, including doctors Manish Soneja, Adil Rashid Khan, Devashish Desai,...

Team India: Responding to adversity with achievement, writes PM Modi

  One of the reasons for the success of India’s Covid-19 inoculation campaign was the trust that people developed in the vaccine and the process followed, writes Prime Minister Narendra Modi. India completed vaccination of 100 crore (one billion) doses on October 21, 2021, in just about nine months since starting vaccination. This has been a tremendous journey in dealing with Covid-19, especially when we recall how things stood in early 2020. Humanity was dealing with such a pandemic after 100 years and no one knew much about the virus. We remember how unpredictable the situation appeared then, as we were faced by an unknown and invisible enemy mutating rapidly. The journey from anxiety to assurance has happened and our nation has emerged stronger, thanks to the world’s largest vaccination drive. It has been a truly ‘bhagirath’ effort involving multiple sections of society. To get a sense of the scale, assume that each vaccination took just two minutes for a healthcare worker. At t...

Production of 1.35 bn vaccine doses between August, December a long haul

  Covishield production to cross 120 mn doses a month, Covaxin 58 mn doses a month Production of both  Covishield  and Covaxin – Covid-19 vaccines from Serum Institute of India (SII) and Bharat Biotech – is set to rise from next month. The target of 1.35 bn vaccine doses between August and December, however, looks like a long haul. According to a response given in the Rajya Sabha, Health Minister Mansukh Mandaviya said recently that the monthly production capacity of Covishield is projected to increase from 110 mn doses to more than 120 mn doses a month, whereas the production capacity of Covaxin is projected to increase from 25 mn doses a month to around 58 mn doses a month. Mandaviya added that apart from this, the Centre has also facilitated further capacity augmentation of Covaxin at central public sector enterprises including Haffkine Biopharmaceutical Corporation Ltd, Mumbai; Indian Immunologicals Limited (IIL), Hyderabad and Bharat Immunological...

Covishield shows better antibody response than Covaxin, says study

  The study was aimed at analysing the antibody response after two complete doses of Covishield and Covaxin in Indians Indian health care workers who were administered Covishield have shown better antibody response than the Covaxin recipients, revealed a recent study. The study, published in an online archive for unpublished manuscripts in medical sciences medRxiv, showed that after two shots of the vaccines, 98 per cent recipients of Covishield showed antibody response, while the same was 80 per cent among Covaxin recipients. The study published by a group of doctors – Awadhesh Kumar Singh, Sanjeev Ratnakar Phatak, Ritu Singh, Kingshuk Bhattacharjee, Nagendra Kumar Singh, Arvind Gupta, and Arvind Sharma – has not been peer-reviewed yet. The researchers have declared no competing interest and that no funding was received for this cross-sectional study. The study was aimed at analysing the antibody response after two complete doses of Covishield and Covaxin in Indians. “We assessed ...

India’s Covid vaccination drive hangs in balance, and so does the world’s

  When the pandemic ends, it will be with the tremendous assistance of India’s pharmaceutical industry. On April 11, India recorded almost 170,000 Covid-19 cases, a record for the country since the start of the pandemic. The day before, India crossed a different kind of milestone: Vaccinating 100 million people. It is this seesaw of despair and hope that India rides today, battling the outbreak with a healthcare system operating on the brink even as its pharmaceutical industry tries to fill the world’s prescription for vaccine doses. India reached the 100 million vaccination mark in 85 days, faster than the U.S. and China, which took 89 and 102 days respectively. But the task ahead is formidable: the government of Prime Minister Narendra Modi has set a target of fully vaccinating 300 million individuals by July. The arithmetic alone is daunting. India started with a stock of 100 million vaccine doses at the beginning of the year. Its two manufacturers– Serum Institute of India ...

South Africa receives 1 million Oxford-AstraZeneca Covid-19 vaccine doses

Ramaphosa said the vaccine would boost the fight against the pandemic South Africa has received the country’s first consignment of 1 million Oxford University-AstraZeneca vaccines which arrived from the Serum Institute of India (SII). President Cyril Ramaphosa, Deputy President David Mabuza and Health Minister Zweli Mkhize, among other officials, lined up on the tarmac of OR Tambo airport to welcome the vaccine cargo, Xinhua news agency reported on Tuesday. Ramaphosa said the vaccine would boost the fight against the pandemic. “Today marks a major milestone in our fight against the coronavirus pandemic as we receive our first consignment of the   Coronavirus vaccine . This batch will benefit our healthcare workers who have been at the forefront of keeping us all safe,” Ramaphosa said. “We thank all South Africans and all the researchers who have contributed toward ensuring the successful development of the vaccine,” he added. The vaccination program was said to be organised and coo...

First Covishield consignment leaves Serum Institute for 13 locations

  Three temperature-controlled trucks rolled out of the Serum Institute gates shortly before 5 am and left for Pune airport A decisive phase in India’s fight against coronavirus began in the wee hours on Tuesday as the first consignment of Covishield vaccines left Serum Institute of India for Pune airport, four days ahead of the nationwide inoculation drive launch. Three temperature-controlled trucks rolled out of the Serum Institute gates shortly before 5 am and left for Pune airport, from where the vaccines will be flown across India. The trucks carried 478 boxes of the vaccines, each box weighing 32 kg, a source involved in the vaccine transport arrangements told PTI. The trucks left the Serum Institute of India premises at Manjari and reached the airport, located 15 km from the facility. From the airport, the vaccines will be dispatched to 13 locations across the country by 10 am, the source said. A ‘puja’ was performed before the vehicles left the facility. The locations where...

Bangladesh approves getting 30 mn doses of Covishield vaccine from India

  Bangladesh approved procurement of 30 million doses of Covishield Covid-19 vaccine from India, co-developed by European pharmaceutical company AstraZeneca and Oxford University Bangladesh on Thursday approved procurement of 30 million doses of Covishield COVID-19 vaccine from India, co-developed by European pharmaceutical company AstraZeneca and Oxford University. Bangladesh drug regulator Directorate General of Drug Administration (DGDA) has authorised Beximco Pharmaceuticals Limited to import and distribute the COVID-19 vaccine from India. In the initial six months of the first phase, Beximco will procure five million vaccine doses per month, reported Dhaka Tribune. “Beximco pharma can now import and distribute the COVID-19 vaccine from India. It will first supply the vaccine in meeting the government’s requirements. Then it can supply the vaccine to private hospitals approved by the government,” said DGDA Deputy Director Md Salauddin. Earlier on Monday, the government issued a...

Covid-19: Sinovac vaccine shows 78% efficacy in Brazil after data confusion

  The protection rate, confirmed by Sao Paulo state officials, was derived from Sinovac’s most advanced final-phase trials in Brazil involving about 13,000 participants The vaccine developed by China’s Sinovac Biotech Ltd. was found to be 78% effective against Covid-19 in late-stage trials in Brazil, the most definitive evidence so far on the shot’s efficacy after previous data sparked doubt and confusion. The protection rate, confirmed by Sao Paulo state officials, was derived from  Sinovac ’s most advanced final-phase trials in Brazil involving about 13,000 participants. Coming after data was withheld at a progress update in late December, the rate is still below the roughly 95% effectiveness seen in cutting-edge mRNA vaccines developed by Pfizer Inc. and Moderna Inc. and being deployed in the U.S. Sinovac’s CoronaVac vaccine was 78% effective in preventing mild cases of Covid-19 and 100% effective against severe and moderate infections, said Dimas Covas, director of the But...

70 mn doses ready: Delays over pricing holding back India’s vaccine rollout

  The Indian government may be looking to put pressure on Serum to lower its prices, as seen by its controversial decision to greenlight a rival vaccine As major countries like the U.S. and China race to vaccinate their populations with rapidly approved shots, tens of millions of doses prepared for India are sitting in storage despite having been authorized for use. While distribution in other nations started soon after approval with pricing deals signed ahead of time, New Delhi and Serum Institute of India Ltd. — the world’s biggest vaccine maker by volume and AstraZeneca Plc’s local partner — have engaged in months of haggling behind closed doors and are yet to sign a formal supply agreement. That has left at least 70 million vaccine doses in limbo despite the urgent need in a country facing the world’s second-largest outbreak. On Sunday, Serum’s billionaire Chief Executive Officer Adar Poonawalla said Indian officials have “orally” agreed to buy 100 million doses at a “special p...